iQS - Theranostics Synthesizer

iQS-TS is a fully automated cassette-based Theranostics Synthesizer facilitating the routine preparation of radiolabeled biomolecules.

The computer controlled iQS-TS module employs predefined labeling protocols for GMP-compliant production of radiolabeled biological tracers like peptides, antibodies, small molecules or hormones, addressing a wide range of targets such as somatostatin receptors, prostate-specific membrane antigen, bone-tissue, bombesin receptors or integrins.

User-friendly click‘n‘start cassettes and reagent sets facilitate intuitive and convenient radiopharmaceutical preparation using the iQS-TS. The consumables are equipped with RFID Tags for automated recognition and reporting of component status (Lot., Expiry) and documentation.

The production of radiopharmaceuticals with the iQS-TS complies with current GMP standards. The module offers simple and intuitive software guided handling, fast production and a convenient filter integrity test. Standards for hygienic design were applied to optimally match clean room conditions. Prior to each synthesis, the self-check takes place. RFID tags assure proper GMP documentation and prevent use of expired consumables. Real-time control and visualization of synthesis steps include volume, temperature and activity control (smart radiochemical yield protection). Despite of all its capabilities the iQS-TS features an unbelievably small footprint of only 26 x 21 x 18 cm without any additional components or installation requirements, like gas supply.
 

Various diagnostic and therapeutic radioisotopes can be used:

•   Lanthanides (¹⁷⁷Lu, ¹⁶¹Tb, ¹⁵³Sm, ¹⁶⁶Ho)
•   Actinides  (²²⁵Ac) as well as
•   ⁶⁸Ga, ⁴⁴Sc, ¹¹¹In, ²¹³Bi, among others